Publications List
1
January 19, 2026
Frontiers in Immunology
Issue (Vol): Pages ::
16:1731315.
Adjunctive GM-CSF therapy enhances host defense against systemic Candida auris infection in immunosuppressed mice
Mattos E.C., Das Gupta K., Quintanilla D., Hautau H., Ibrahim A.S. and Singh S.
2
March 12, 2026
Journal of Medicinal Chemistry
Issue (Vol): Pages ::
69(5):6179-6198.
Selectivity Modulation of Small Cationic Membrane-Active Cyclic Peptides with Broad-Spectrum Activity against Bacteria and Fungi
Lohan S, Tiwari RK, Maslennikov I, Das Gupta K, Singh S, Parang K.
3
December 15, 2025
Scientific Reports
Issue (Vol): Pages ::
16 (2582)
Next-generation Candida albicans vaccine VXV-01 containing recombinant Als3p and Hyr1p antigens for invasive Candida infections
Singh S, Youssef EG, Barbarino A, Hautau H, Nabeela S, Gebremariam T, Alkhazraji S, Ostroff G, Christensen D, Cochrane T, Ibrahim AS.
4
2026, May 16
NPJ Vaccine
Issue (Vol): Pages ::
ahead of print
β-Glucan Chitosan Particle Provides Cross-Protection Against Multi-Drug-Resistant Candida auris
Singh S, Barbarino A, Youssef EG, Das Gupta K, Nabeela S, Gebremariam T, Alkhazraji S, Uppuluri P, Ostroff G, Ibrahim AS.
5
July 1, 2025
Nature Communications
Issue (Vol): Pages ::
16(1):5673.
Adhesin Als4112 promotes Candida auris skin colonization through interactions with keratinocytes and extracellular matrix proteins
Zhao G, Lyu J, Veniaminova NA, Zarnowski R, Mattos E, Johnson CJ, Quintanilla D, Hautau H, Hold LA, Xu B, Anku JAE, Dasgupta K, Hale JJ, Steltzer SS, Santana DJ, Ibrahim AS, Snitkin ES, Andes D, Nett JE, Singh S, Abraham AC, Killian ML, Kahlenberg JM, Wong SY, O'Meara TR.
6
June 30, 2025
mBio
Issue (Vol): Pages ::
e0084925.
A spatial transcriptomic atlas of the host response to oropharyngeal candidiasis
Nabeela S, McSwiggin H, Magalhaes RDM, Mattos EC, Mannan M, Dillon JT, Barbarino A, Youssef EG, Singh S, Yan W, Ibrahim AS, Conti HR, Uppuluri P.
7
March 12, 2025
Science Translational Medicine
Issue (Vol): Pages ::
17(789):eads7369.
A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response
Gu Y, Singh S, Alqarihi A, Alkhazraji S, Gebremariam T, Youssef EG, Liu H, Fan X, Jiang WR, Andes D, Cochrane TR, Schwartz JA, Filler SG, Uppuluri P, Ibrahim AS.
8
September 29, 2023
Science
Issue (Vol): Pages ::
381(6665):1461-1467.
A Candida auris-specific adhesin, Scf1, governs surface association, colonization, and virulence
Santana D.J., Anku J.A.E., Zhao G., Zarnowski R., Johnson C.J., Hautau H., Visser N.D., Ibrahim A.S., Andes D., Nett J.E., Singh S.*, O'Meara T.R.
9
August 23, 2023
PLoS Pathogens
Issue (Vol): Pages ::
19(8):e1011579.
Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection
Phan Q.T., Solis N.V., Cravener M.V., Swidergall M., Lin J., Huang M.Y., Liu H., Singh S., Ibrahim A.S., Mazzone M., Mitchell A.P., Filler S.G.
10
January 11, 2023
Journal of Fungi
Issue (Vol): Pages ::
12;9(1):103.
Protective efficacy of Anti-Hyr1p Monoclonal Antibody against systemic candidiasis due to multidrug-resistant Candida auris
Singh S., Barbarino A., Youssef E.G., Coleman D., Gebremariam T.., Ibrahim AS.
11
August 17, 2022
PLoS Biology
Issue (Vol): Pages ::
20(8):e3001762.
Niclosamide loaded Eudragit EPO nanoparticles show enhanced Candida biofilm penetration, trigger biofilm detachment and protect from mucosal candidiasis
Sutar Y., Nabeela S., Singh S., Alqarihi A., Solis N., Filler S., Gebremariam T., Ibrahim A.S., Date A.
12
July 22, 2022
Frontiers in Immunology
Issue (Vol): Pages ::
13:925821.
Antibodies targeting Candida albicans Als3 and Hyr1 antigens protect neonatal mice from candidiasis
Singh S., Nabeela S., Barbarino A., Ibrahim A.S., Uppuluri P.
13
July 7, 2022
PLoS Pathogens
Issue (Vol): Pages ::
18(7):e1010681.
Serum-bridging molecules drive Candidal invasion of human but not mouse endothelial cells
Phan Q.T., Solis N.V., Lin J., Swidergall M., Singh S., Liu H., Sheppard D.C., Ibrahim A.S., Mitchell A.P., Filler S.G.
14
July 15, 2021
Journal of Antimicrobial Chemotherapy
Issue (Vol): Pages ::
76(10):2636-2639.
Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis
Gebremariam T., Gu Y., Singh S., Kitt T.M., Ibrahim A.S.
15
July 14, 2021
Nature
Issue (Vol): Pages ::
596(7870):114-118.
Adaptive immunity promotes a mutually beneficial interaction between commensal eukaryotes
Ost K., O' Meara T.R., Stephens W.Z., Chiaro T., Zhou H., Penman J., Bell R., Catanzaro J.R., Song D., Singh S., Call D.H., Hwang-Wong E., Hanson K.E., Valentine J.F., Christensen K.A., O' Connell R.M., Cormack B., Ibrahim A.S., Palm N.W., Noble S.M. & Round J.L.
16
March 15, 2021
PLoS Biology
Issue (Vol): Pages ::
19(3):e3000957.
An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans
Mamouei Z., Singh S., Lemire B., Gu Y., Alqarihi A., Nabeela S., Li D., Ibrahim A.S., Uppuluri P.
17
January 18, 2021
Nature Microbiology
Issue (Vol): Pages ::
6(3):313-326.
Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis
Soliman S.S.M.*, Baldin C.*, Gu Y.*, Singh S.*, Gebremariam T., Swidergall M., Alqarihi A., Youssef E.G., Alkhazraji S., Pikoulas A., Perske C., Venkataramani V., Rich A., Bruno V.M., Hotopp J.D., Mantis N.J., Edwards Jr. J.E., Filler S.G., Chamilos G., Vitetta E.S., Ibrahim A.S.
18
December 22, 2020
Nature Communications
Issue (Vol): Pages ::
11(1):6429.
Novel 3,3-diarylated oxindole efflux inhibitor provides a promising approach to combat azole resistance in the emerging fungal pathogen Candida auris
Iyer K.A., Camara K., Daniel-Ivadd M., Trilles R., Pimentel-Elardod S.M., Fossen J.L., Marchillo K., Liu Z, Singh S.., Munoz J.F., Kim S.H., Porco J.A. Jr., Cuomo C.A., Williams N.S., Ibrahim A.S., Edwards J.E. Jr, Andes D.R., Nodwell J.R., Brown L.E., Whitesell L., Robbins N., Cowen L.E.
19
July 7, 2020
Frontiers in Immunology
Issue (Vol): Pages ::
11:1408.
Editorial: Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies
Singh S., Yanow S. and Agrawal B.
20
February 18, 2020
Frontiers in Immunology
Issue (Vol): Pages ::
11:76.
Monoclonal IgM antibodies raised against Candida albicans Hyr1 provide cross-kingdom protection against Gram-negative bacteria
Youssef E.G., Zhang L., Alkhazraji S., Ghebremariam T., Singh S., Yount N.Y., Yeaman M.R., Uppuluri P., Ibrahim A.S.
21
December 9, 2019
Antimicrobial Agents and Chemotherapy
Issue (Vol): Pages ::
64(3):e01735-19.
Fosmanogepix is effective in treating immunocompromised mice infected with invasive pulmonary scedosporiosis or disseminated fusariosis
Alkhazraji S., Gebremariam T., Alqarihi A., Gu Y., Mamouei Z., Singh S., Wiederhold N., Shaw K.J. and Ibrahim A.S.
22
November 4, 2019
Antimicrobial Agents and Chemotherapy
Issue (Vol): Pages ::
20;64(1):e01966-19.
Galactomannan is a biomarker of fosmanogepix efficacy in treating experimental invasive pulmonary aspergillosis
Gebremariam T., Alkhazraji S., Gu Y., Singh S., Alqarihi A., Shaw K.J., Ibrahim A.S.
23
August 5, 2019
PLoS Pathogens
Issue (Vol): Pages ::
15(8): e1007460.
The NDV-3A vaccine protects mice from multidrug-resistant Candida auris infection
Singh S., Uppuluri P., Mamouei Z., Alqarihi A., Elhassan H., French S., Lockhart S.R., Chiller T., Edwards Jr. J.E., Ibrahim A.S.
24
May 25, 2019
Cells
Issue (Vol): Pages ::
26;8(5): 507.
Heterologous immunity between adenoviruses and hepatitis C virus: Recombinant adenovirus vaccine vectors containing antigens from unrelated pathogens induce cross-reactive immunity against HCV antigens
Agrawal B., Gupta N., Vedi S., Singh S., Li W., Garg S., Li J., Kumar R.
25
April 17, 2019
Scientific Reports
Issue (Vol): Pages ::
17;9(1):6194.
NDV-3A vaccination prevents Candida albicans colonization of jugular vein catheters in mice
Alqarihi A.*, Singh S.*, Edwards Jr. J.E., Ibrahim A.S., Uppuluri P.
26
October 31, 2018
mSphere
Issue (Vol): Pages ::
3(5):e00539-18.
Alexidine dihydrochloride has broad-spectrum activities against diverse fungal pathogens
Mamouei Z., Alqarihi A., Singh S., Shuying X., Mansour M.K., Ibrahim A.S., and Uppuluri P.
27
July 17, 2018
Journal of Virology
Issue (Vol): Pages ::
92(15): :e00281-18.
DNA and protein co-immunization regimens combined with different Toll-like receptor-4 based adjuvants induce immune responses controlling SIVsmE660 infection
Singh S., Ramirez E., Doueiri R., Valentin A., Rosati M., Hu X., Keele B.F., Shen X., Tomaras G.D., Ferrari G., LaBranche C., Montefiori D.C., Das J., Alter G., Trinh H.V., Hamlin C., Rao M., Dayton F., Bear J., Chowdhury B., Alicea C., Lifson J.D., Broderick K.E., Sardesai N.Y., Sivananthan S.J., Fox C.B., Reed S.G., Venzon D.J., Hirsch V.M., Pavlakis G.N., Felber B.K.
28
June 15, 2018
Frontiers in Immunology
Issue (Vol): Pages ::
9:1349.
Human Als3p antibodies are surrogate markers of NDV-3A vaccine efficacy against recurrent vulvovaginal candidiasis
Uppuluri P., Singh S.*, Alqarihi A., Schmidt C.S., Hennessey J.P., Yeaman M.R, Filler S.G., Edwards J.E., and Ibrahim A.S.
29
July 27, 2017
International Journal of Molecular Sciences
Issue (Vol): Pages ::
18(8):1626.
Unsolved Puzzles Surrounding HCV Immunity: Heterologous Immunity Adds Another Dimension
Agrawal B., Singh S., Gupta N., Li W., Vedi S., and Kumar R.
30
January 11, 2016
PLoS ONE
Issue (Vol): Pages ::
11(1): e0146404.
Heterologous immunity between adenoviruses and hepatitis C virus: A new paradigm in HCV immunity and vaccines
Singh S., Vedi S., Samrat S.K., Li W., Kumar R., and Agrawal B.
31
November 9, 2015
Frontiers in Immunology
Issue (Vol): Pages ::
6:599.
Editorial: Influenza Virus Vaccines and Immunotherapies
Kumar A.*, and Singh S.*
32
July 2, 2015
Viral Immunology
Issue (Vol): Pages ::
28(6): 309-24.
Immunization with recombinant adenoviral vectors expressing HCV core or F proteins leads to T cells with reduced effector molecules granzyme B and IFN-_
Samrat S.K., Vedi S., Li W., Singh S., Samrat S.K., Kumar R., and Agrawal B.
33
May 13, 2014
Vaccine
Issue (Vol): Pages ::
13;32(23):2712-21.
Recombinant adenoviral vector expressing HCV NS4 induces protective immune responses in a mouse model of vaccinia-HCV virus infection
Singh S., Vedi S., Li W., Samrat S.K., Kumar R., Agrawal B.
34
February 3, 2014
Vaccine
Issue (Vol): Pages ::
2(6): 651-6.
Transplacental rotavirus IgG interferes with immune response to live oral rotavirus vaccine ORV-116E in Indian infants
Appaiahgari M.B., Glass R., Singh S.*, Taneja S., Chandola T.R., Bhandari N., Mishra S., and Vrati S.
35
January 27, 2014
PLoS ONE
Issue (Vol): Pages ::
9(1): e86567.
Alternate reading frame protein (F protein) of hepatitis C virus: Paradoxical effects of activation and apoptosis on human dendritic cells lead to stimulation of T cells
Samrat S.K., Li W., Singh S., Kumar R., and Agrawal B.
36
January 8, 2013
Epidemiology and Infection
Issue (Vol): Pages ::
141(10): 2094-100.
Descriptive epidemiology of rotavirus infection in a community in North India
Chandola T.R., Taneja S., Goyal N., Rathore S.S., Appaiahgari M.B., Mishra A., Singh S.*, and Vrati S. and Bhandari N.
37
August 1, 2009
The Journal of Infectious Diseases
Issue (Vol): Pages ::
200(3): 421-9.
A dose-escalation safety and immunogenicity study of live attenuated oral rotavirus vaccine 116E in infants: a randomized, double-blind, placebo-controlled trial
Bhandari N., Sharma P., Taneja S., Kumar T., Rongsen-Chandola T., Appaiahgari M.B., Mishra A., Singh S.*, Vrati S., and Rotavirus Vaccine Development Group.
Books and Chapters
6
Chapter
Sarkar A, Kundu S, Singh S, and Sen S (2018). Data Mining in Nutrigenomics. In Shampa Sen, Leonid Datta and Sayak Mitra, eds. Machine Learning and IoT: A Biological Perspective. (pp 40-53). New York, USA: CRC Press, Taylor & Francis Group. ISBN 9781138492691.
5
Chapter
Singh S, Kumar R, and Agrawal B (2018). Future of Adenoviruses as Vaccine Vector. In Yulia A Desheva (eds.) Adenoviruses, London, United Kingdom: Intech Publishers.
4
Chapter
Singh S, Ibrahim AS, Edwards JE (2019). Candida auris: An emerging multidrug-resistant Candida species. In J. Larry Jameson, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, Dan L. Longo, Joseph Loscalzo (eds.) Harrison's Principles of Internal Medicine, 20th Edition. McGraw Hill Publishers.
3
Chapter
Lionakis MS, Singh S, Ibrahim AS, Edwards JE (2022). Chapter: 216. Candidiasis. In Dennis L. Kasper and Anthony S. Fauci (eds.) Harrison's Principal’s of Internal Medicine. McGraw Hill Publishers, 21st Edition, ISBN: 978-1-264-26846-7.
2
eBook
Agrawal B, Yanow S, Singh S, eds. (2020). Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies. Lausanne: Frontiers Media SA. ISSN 1664-8714. ISBN 978-2-88963-965-6.
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